Publicaciones

2018

DeGregorio-Rocasolano N., Martí-Sistac O., Ponce J., Castelló-Ruiz M., Millán M., Guirao V., García-Yébenes I., Salom JB., Ramos-Cabrer P., Alborch E., Lizasoain I., Castillo J., Dávalos A., Gasull T. "Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage". Redox Biology. 15:143-158. 2018

Horcajo P., Xia D., Randle N., Collantes-Fernández E., Wastling J., Ortega-Mora LM., Regidor-Cerrillo J. "Integrative transcriptome and proteome analyses define marked differences between Neospora caninum isolates throughout the tachyzoite lytic cycle". Journal of Proteomics. 180:108-119. 2018

Moreno E., Chiarlone A., Medrano M., Puigdellívol M., Bibic L., Howell LA., Resel E., Puente N., Casarejos MJ., Perucho J., Botta J., Suelves N., Ciruela F., Ginés S., Galve-Roperh I., Casadó V., Grandes P., Lutz B., Monory K., Canela EI., Lluís C., McCormick PJ., Guzmán M. "Singular Location and Signaling Profile of Adenosine A2A-Cannabinoid CB1 Receptor Heteromers in the Dorsal Striatum". Neuropsychopharmacology. 43(5):964-977. 2018

Jiménez-Reinoso A., Marin AV., Subias M., López-Lera A., Román-Ortiz E., Payne K., Ma CS., Arbore G., Kolev M., Freeley SJ., Kemper C., Tangye SG., Fernández-Malavé E., Rodríguez de Córdoba S., López-Trascasa M., Regueiro JR. "Human plasma C3 is essential for the development of memory B, but not T, lymphocytes". Journal of Allergy and Clinical Immunology. 141(3):1151-1154.e14. 2018

Harwood SL., Alvarez-Cienfuegos A., Nuñez-Prado N., Compte M., Hernández-Pérez S., Merino N., Bonet J., Navarro R., Van Bergen en Henegouwen PMP., Lykkemark S., Mikkelsen K., Mølgaard K., Jabs F., Sanz L., Blanco FJ., Roda-Navarro P., Alvarez-Vallina L. "ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy". OncoImmunology. 7(1):e1377874. 2018

Campero LM., Moreno-Gonzalo J., Venturini MC., Moré G., Dellarupe A., Rambeaud M., Echaide IE., Valentini B., Campero CM., Moore DP., Cano DB., Fort M., Mota RA., Serrano-Martínez ME., Cruz-Vázquez C., Ortega-Mora LM., Álvarez-García G. "An Ibero-American inter-laboratory trial to evaluate serological tests for the detection of anti-Neospora caninum antibodies in cattle". Tropical Animal Health and Production. 50(1):75-84. 2018

2017

García-Cárceles J., Decara JM., Vázquez-Villa H., Rodríguez R., Codesido E., Cruces J., Brea J., Loza MI., Alén F., Botta J., McCormick PJ., Ballesteros JA., Benhamú B., Rodríguez de Fonseca F., López-Rodríguez ML. "A Positive Allosteric Modulator of the Serotonin 5-HT 2C Receptor for Obesity". Journal of Medicinal Chemistry. 60(23):9575-9584. 2017

Lopez Exposito P., Blanco A., Negro C. "Estimating fractal dimension of microalgal flocs through confocal laser scanning microscopy and computer modelling". Algal Research. 28:74-79. 2017

Martinez VG., Ontoria-Oviedo I., Ricardo CP., Harding SE., Sacedon R., Varas A., Zapata A., Sepulveda P., Vicente A. "Overexpression of hypoxia-inducible factor 1 alpha improves immunomodulation by dental mesenchymal stem cells". Stem Cell Research & Therapy. 8(1):208. 2017

Mateo Y., Johnson KA., Covey DP., Atwood BK., Wang H., Zhang S., Gildish I., Cachope R., Bellocchio L., Guzmán M., Morales M., Cheer JF., Lovinger DM. "Endocannabinoid Actions on Cortical Terminals Orchestrate Local Modulation of Dopamine Release in the Nucleus Accumbens". Neuron. 96(5):1112-1126.e5. 2017

Palma-Tortosa S., García-Culebras A., Moraga A., Hurtado O., Perez-Ruiz A., Durán-Laforet V., Parra Jdl., Cuartero MI., Pradillo JM., Moro MA., Lizasoain I. "Specific Features of SVZ Neurogenesis After Cortical Ischemia: a Longitudinal Study". Scientific Reports. 7(1):16343. 2017

Vargas-Caraveo A., Sayd A., Maus SR., Caso JR., Madrigal JLM., García-Bueno B., Leza JC. "Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions". Scientific Reports. 7(1):13113. 2017

González-Vera JA., Medina RA., Martín-Fontecha M., Gonzalez A., de la Fuente T., Vázquez-Villa H., García-Cárceles J., Botta J., McCormick PJ., Benhamú B., Pardo L., López-Rodríguez ML. "A new serotonin 5-HT6 receptor antagonist with procognitive activity – Importance of a halogen bond interaction to stabilize the binding". Scientific Reports. 7(1):41293. 2017

Troupiotis-Tsaïlaki A., Zachmann J., González-Gil I., Gonzalez A., Ortega-Gutiérrez S., López-Rodríguez ML., Pardo L., Govaerts C. "Ligand chain length drives activation of lipid G protein-coupled receptors". Scientific Reports. 7(1):2020. 2017

Gutiérrez-Expósito D., García-Bocanegra I., Howe DK., Arenas-Montes A., Yeargan MR., Ness SL., Ortega-Mora LM., Álvarez-García G. "A serosurvey of selected cystogenic coccidia in Spanish equids: first detection of anti-Besnoitia spp. specific antibodies in Europe". BMC Veterinary Research. 13(1):128. 2017

Jiménez-Pelayo L., García-Sánchez M., Regidor-Cerrillo J., Horcajo P., Collantes-Fernández E., Gómez-Bautista M., Hambruch N., Pfarrer C., Ortega-Mora LM. "Differential susceptibility of bovine caruncular and trophoblast cell lines to infection with high and low virulence isolates of Neospora caninum". Parasites & Vectors. 10(1):463. 2017

Martínez VG., Rubio C., Martínez-Fernández M., Segovia C., López-Calderón F., Garín MI., Teijeira A., Munera-Maravilla E., Varas A., Sacedón R., Guerrero F., Villacampa F., de la Rosa F., Castellano D., López-Collazo E., Paramio JM., Vicente Á., Dueñas M. "BMP4 Induces M2 Macrophage Polarization and Favors Tumor Progression in Bladder Cancer". Clinical Cancer Research. 23(23):7388-7399. 2017

Maycas M., Portolés MT., Matesanz MC., Buendía I., Linares J., Feito MJ., Arcos D., Vallet-Regí M., Plotkin LI., Esbrit P., Gortázar AR. "High glucose alters the secretome of mechanically stimulated osteocyte-like cells affecting osteoclast precursor recruitment and differentiation". Journal of Cellular Physiology. 232(12):3611-3621. 2017

Diezma-Díaz C., Jiménez-Meléndez A., Fernández M., Gutiérrez-Expósito D., García-Lunar P., Ortega-Mora LM., Pérez-Salas JA., Blanco-Murcia J., Ferre I., Álvarez-García G. "Bovine chronic besnoitiosis in a calf: Characterization of a novel B. besnoiti isolate from an unusual case report". Veterinary Parasitology. 247:10-18. 2017

Montero-Herradón S., García-Ceca J., Zapata AG. "EphB receptors, mainly EphB3, contribute to the proper development of cortical thymic epithelial cells". Organogenesis. 13(4):192-211. 2017

García-Ceca J., Montero-Herradón S., Alfaro D., Zapata AG. "Increased epithelial-free areas in thymuses with altered EphB-mediated thymocyte–thymic epithelial cell interactions". Histochemistry and Cell Biology. 148(4):381-394. 2017

Horcajo P., Jiménez-Pelayo L., García-Sánchez M., Regidor-Cerrillo J., Collantes-Fernández E., Rozas D., Hambruch N., Pfarrer C., Ortega-Mora LM. "Transcriptome modulation of bovine trophoblast cells in vitro by Neospora caninum". International Journal for Parasitology. 47(12):791-799. 2017

Hemphill A., Leitão A., Ortega-Mora L., Cooke BM. "ApiCOWplexa 2017 – 4th International Meeting on Apicomplexan Parasites in Farm Animals". International Journal for Parasitology. 47(12):697-699. 2017

Gutiérrez-Expósito D., Ferre I., Ortega-Mora LM., Álvarez-García G. "Advances in the diagnosis of bovine besnoitiosis: current options and applications for control". International Journal for Parasitology. 47(12):737-751. 2017

Jiménez-Meléndez A., Ojo KK., Wallace AM., Smith TR., Hemphill A., Balmer V., Regidor-Cerrillo J., Ortega-Mora LM., Hehl AB., Fan E., Maly DJ., Van Voorhis WC., Álvarez-García G. "In vitro efficacy of bumped kinase inhibitors against Besnoitia besnoiti tachyzoites". International Journal for Parasitology. 47(12):811-821. 2017

San-Miguel Ayanz JM., Garcia-Peña FJ., García-Lunar P., Ortega-Mora LM., Ruano MJ., Álvarez-García G., Collantes-Fernández E. "Seroprevalence of Leptospirosis, Brucellosis, and Q Fever in a Wild Red Deer ( Cervus elaphus ) Population Kept in a Fenced Reserve in Absence of Contact with Livestock". Vector-Borne and Zoonotic Diseases. 17(10):692-697. 2017

Cicuéndez M., Silva VS., Hortigüela MJ., Matesanz MC., Vila M., Portolés MT. "MC3T3-E1 pre-osteoblast response and differentiation after graphene oxide nanosheet uptake". Colloids and Surfaces B: Biointerfaces. 158:33-40. 2017

García-Lunar P., Ortega-Mora LM., Schares G., Diezma-Díaz C., Álvarez-García G. "A new lyophilized tachyzoite based ELISA to diagnose Besnoitia spp. infection in bovids and wild ruminants improves specificity". Veterinary Parasitology. 244:176-182. 2017

Feliú A., Bonilla del Río I., Carrillo-Salinas FJ., Hernández-Torres G., Mestre L., Puente N., Ortega-Gutiérrez S., López-Rodríguez ML., Grandes P., Mecha M., Guaza C. "2-Arachidonoylglycerol Reduces Proteoglycans and Enhances Remyelination in a Progressive Model of Demyelination". The Journal of Neuroscience. 37(35):8385-8398. 2017

Valera JS., Sánchez-Naya R., Ramírez FJ., Zafra JL., Gómez R., Casado J., Sánchez L. "Solvent-Directed Helical Stereomutation Discloses Pathway Complexity on N-Heterotriangulene-Based Organogelators". Chemistry - A European Journal. 23(46):11141-11146. 2017

Porto WJN., Horcajo P., Kim PdCP., Regidor-Cerrillo J., Romão EA., Álvarez-García G., Mesquita EPd., Mota RA., Ortega-Mora LM. "Peripheral and placental immune responses in goats after primoinfection with Neospora caninum at early, mid and late gestation". Veterinary Parasitology. 242:38-43. 2017

Müller J., Aguado-Martínez A., Ortega-Mora L., Moreno-Gonzalo J., Ferre I., Hulverson MA., Choi R., McCloskey MC., Barrett LK., Maly DJ., Ojo KK., Van Voorhis W., Hemphill A. "Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosis". Journal of Antimicrobial Chemotherapy. 72(8):2334-2341. 2017

Castro-Sánchez P., Ramirez-Munoz R., Lamana A., Ortiz A., González-Álvaro I., Roda-Navarro P. "mRNA profilin identifies low levels of phosphatases dual-specific phosphatase-7 (DUSP7) and cell division cycle-25B (CDC25B) in patients with early arthritis". Clinical & Experimental Immunology. 189(1):113-119. 2017

Torres I., Díaz-Ortiz A., Sánchez L., Orduna J., Blesa MJ., Carrillo JR., Prieto P. "Tunable emission in aggregated T-Shaped 2 H -Benzo[ d ][1,2,3]triazoles with waveguide behaviour". Dyes and Pigments. 142:212-225. 2017

Benavides J., Fernández M., Castaño P., Ferreras MC., Ortega-Mora L., Pérez V. "Ovine Toxoplasmosis: A New Look at its Pathogenesis". Journal of Comparative Pathology. 157(1):34-38. 2017

García-Culebras A., Palma-Tortosa S., Moraga A., García-Yébenes I., Durán-Laforet V., Cuartero MI., de la Parra J., Barrios-Muñoz AL., Díaz-Guzmán J., Pradillo JM., Moro MA., Lizasoain I. "Toll-Like Receptor 4 Mediates Hemorrhagic Transformation After Delayed Tissue Plasminogen Activator Administration in In Situ Thromboembolic Stroke". Stroke. 48(6):1695-1699. 2017

Hernández-Jiménez M., Peña-Martínez C., Godino MdC., Díaz-Guzmán J., Moro MÁ., Lizasoain I., Ahmad M. "Test repositioning for functional assessment of neurological outcome after experimental stroke in mice". PLOS ONE. 12(5):e0176770. 2017

Fernández-Trapero M., Espejo-Porras F., Rodríguez-Cueto C., Coates JR., Pérez-Díaz C., de Lago E., Fernández-Ruiz J. "Upregulation of CB 2 receptors in reactive astrocytes in canine degenerative myelopathy, a disease model of amyotrophic lateral sclerosis". Disease Models & Mechanisms. 10(5):551-558. 2017

Buendía J., Calbo J., Ortí E., Sánchez L. "Flexible Chirality in Self-Assembled N -Annulated Perylenedicarboxamides". Small. 13(20):1603880. 2017

OLIVEIRA S., SOARES RM., AIZAWA J., SOARES HS., CHIEBAO DP., ORTEGA-MORA LM., REGIDOR-CERRILLO J., SILVA NQB., GENNARI SM., PENA HFJ. "Isolation and biological and molecular characterization of Neospora caninum (NC-SP1) from a naturally infected adult asymptomatic cattle (Bos taurus) in the state of São Paulo, Brazil". Parasitology. 144(06):707-711. 2017

Valencia J., Jiménez E., Martínez VG., Del Amo BG., Hidalgo L., Entrena A., Fernández-Sevilla LM., Del Río F., Varas A., Vicente Á., Sacedón R. "Characterization of human fibroblastic reticular cells as potential immunotherapeutic tools". Cytotherapy. 19(5):640-653. 2017

Rodríguez-Cueto C., Hernández-Gálvez M., Hillard CJ., Maciel P., Valdeolivas S., Ramos JA., Gómez-Ruiz M., Fernández-Ruiz J., Borchelt DR. "Altered striatal endocannabinoid signaling in a transgenic mouse model of spinocerebellar ataxia type-3". PLOS ONE. 12(4):e0176521. 2017

Jiménez-Reinoso A., Marin AV., Regueiro JR. "Complement in basic processes of the cell". Molecular Immunology. 84:10-16. 2017

Gazzonis AL., Alvarez Garcia G., Maggioni A., Zanzani SA., Olivieri E., Compiani R., Sironi G., Ortega Mora LM., Manfredi MT. "Serological dynamics and risk factors of Besnoitia besnoiti infection in breeding bulls from an endemically infected purebred beef herd". Parasitology Research. 116(4):1383-1393. 2017

Müller J., Aguado-Martínez A., Balmer V., Maly DJ., Fan E., Ortega-Mora L., Ojo KK., Van Voorhis WC., Hemphill A. "Two Novel Calcium-Dependent Protein Kinase 1 Inhibitors Interfere with Vertical Transmission in Mice Infected with Neospora caninum Tachyzoites". Antimicrobial Agents and Chemotherapy. 61(4):e02324-16. 2017

Pradillo JM., Murray KN., Coutts GA., Moraga A., Oroz-Gonjar F., Boutin H., Moro MA., Lizasoain I., Rothwell NJ., Allan SM. "Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia". Brain, Behavior, and Immunity. 61:117-126. 2017

López Expósito P., Blanco Suárez A., Negro Álvarez C. "Laser reflectance measurement for the online monitoring of Chlorella sorokiniana biomass concentration". Journal of Biotechnology. 243:10-15. 2017

Marín-Ramos NI., Piñar C., Vázquez-Villa H., Martín-Fontecha M., González Á., Canales Á., Algar S., Mayo PP., Jiménez-Barbero J., Gajate C., Mollinedo F., Pardo L., Ortega-Gutiérrez S., Viso A., López-Rodríguez ML. "Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling". Chemistry - A European Journal. 23(7):1676-1685. 2017

Marin AV., Jiménez-Reinoso A., Briones AC., Muñoz-Ruiz M., Aydogmus C., Pasick LJ., Couso J., Mazariegos MS., Alvarez-Prado AF., Blázquez-Moreno A., Cipe FE., Haskologlu S., Dogu F., Morín M., Moreno-Pelayo MA., García-Sánchez F., Gil-Herrera J., Fernández-Malavé E., Reyburn HT., Ramiro AR., Ikinciogullari A., Recio MJ., Regueiro JR., Garcillán B. "Primary T-cell immunodeficiency with functional revertant somatic mosaicism in CD247". Journal of Allergy and Clinical Immunology. 139(1):347-349.e8. 2017

Bravo-Ferrer I., Cuartero MI., Zarruk JG., Pradillo JM., Hurtado O., Romera VG., Díaz-Alonso J., García-Segura JM., Guzmán M., Lizasoain I., Galve-Roperh I., Moro MA. "Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke". Stroke. 48(1):204-212. 2017

Gutiérrez-Expósito D., Ortega-Mora LM., Ara V., Marco I., Lavín S., Carvajal-Valilla J., Morales A., Álvarez-García G. "Absence of antibodies specific to Besnoitia spp. in European sheep and goats from areas in Spain where bovine besnoitiosis is endemic". Parasitology Research. 116(1):445-448. 2017

2016

Díaz-Alonso J., de Salas-Quiroga A., Paraíso-Luna J., García-Rincón D., Garcez PP., Parsons M., Andradas C., Sánchez C., Guillemot F., Guzmán M., Galve-Roperh I. "Loss of Cannabinoid CB 1 Receptors Induces Cortical Migration Malformations and Increases Seizure Susceptibility". Cerebral Cortex. In press